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24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

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Marie Bouilloud


Courriel : m_bouilloud(at)
Sujet : Étude des relations entre biodiversité et santé à travers les interactions rongeurs-microbiote-agents zoonotiques
Dates : 1er juillet 2020 – 30 juin 2023
Encadrement CBGP : N. Charbonnel
Université :

Dans le contexte de larges perturbations des écosystèmes, comprendre les relations entre la biodiversité et les maladies infectieuses zoonotiques représente un défi scientifique majeur aux conséquences sociétales importantes auquel les chercheurs doivent répondre afin de pouvoir informer les politiques publiques.

Ce projet de doctorat vise à comprendre les relations biodiversité-santé à travers l’étude des communautés de rongeurs et des agents de zoonoses qu’ils transmettent. Pour cela, nous étudierons les forêts tempérées où les rongeurs y sont abondants et les contacts entre la population humaine et la faune sauvage peuvent être importants.

Ce projet de thèse propose de combiner des approches de terrain, de biologie moléculaire (metabarcoding bactérien) et de modélisation pour analyser les relations entre la diversité des communautés de rongeurs et le risque zoonotique. Trois aspects seront particulièrement approfondis: i) l’impact des co-infections sur l’épidémiologie de certaines zoonoses, ii) les interactions entre la flore bactérienne commensale et la sensibilité des rongeurs aux agents zoonotiques, et iii) la variabilité temporelle (inter-saison, inter-annuelle) des relations biodiversité-santé.