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Last update: May 2021

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Jules Romieu


Courriel : jules.romieu(at)
Sujet : Comment identifier la part de l'introgression due à la sélection ?
Dates : 1er octobre 2021 - 30 septembre 2024
Directeur de thèse : François Rousset
Encadrement CBGP : R. Leblois et M. de Navascués
Université : Université de Montpellier

L’introgression désigne le phénomène de transfert de matériel génétique d’une espèce (ou une population) dans le patrimoine génétique d’une autre par hybridation puis rétrocroisements successifs. Si l’introgression apporte un avantage sélectif à l’espèce réceptrice, on parle alors d’introgression adaptative (AI). Dans ce contexte, ma thèse vise à développer et à tester différentes approches méthodologiques pour identifier les régions sous introgression adaptative.

Dans un premier temps, je développerai une méthode d’inférence basée sur la simulation explorant les variations du niveau d’introgression entre régions nucléaires neutres et adaptatives. Dans un deuxième temps, je concevrai une méthode inférentielle par simulation pour identifier directement les régions sous IA. L’analyse des données génomiques du complexe d’espèces de lézards (genre Podarcis) s’hybridant dans la péninsule ibérique me permettra de tester les différentes méthodes développées sur un jeu de données réel.