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24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Post-doc Marta Avramova

Genetic bases of Saccharomyces cerevisiae nitrogen requirement in winemaking context

My project is a part of the programm Nitrogènes supervised by Bruno Blondin (Montpellier SupAgro, UMR SPO).

Alcoholic fermentation conduction is strongly impacted by the availability of nitrogen in the fermentation environment. In particular, low nitrogen availability could lead to sluggish or unfinished fermentations. The capacity of a Saccharomyces cerevisiae strain to ferment in nitrogen-poor environment would depend on the nitrogen requirement of this same strain. In this context, the NitroGènes project aims to identify key genes involved in nitrogen requirements of S. cerevisiae by the means of a QTL (Quantitative Trait Loci) approach. This would allow the identification of genes involved in nitrogen requirement which would further lead to the evaluation of the impact of different alleles of interest on the fermentation capacity. Also, the distribution of those alleles of interest would be examined in populations of S. cerevisiae strains from different fermentation environments. Thus, the exploitation of the alleles of interest for an improvement of the fermentation capacity of yeast strains in low-nitrogen environment would be examined.


Main publications :

Avramova, M., Cibrario, A., Peltier, E., Coton, M., Coton, E., Schacherer, J., … Masneuf-Pomarede, I. (2018). Brettanomyces bruxellensis population survey reveals a diploid-triploid complex structured according to substrate of isolation and geographical distribution. Scientific Reports, 8(1).

Avramova, M., Vallet-Courbin, A., Maupeu, J., Masneuf-Pomarède, I., & Albertin, W. (2018). Molecular diagnosis of Brettanomyces bruxellensis’ sulfur dioxide sensitivity through genotype specific method. Frontiers in Microbiology, 9(JUN).